You following article gives step-by-step instructions on how to install SyncBack and create your first profile:

If you are currently running SyncBack, close down the program* making sure it is not running in the background, and also that it does not have a scheduled task that is about to commence.

Start the installation program.

Copy and paste your serial number below into the text field to the right of the key symbol on the evaluation screen, then click OK. If you have upgraded from SyncBackSE to SyncBackPro then you need to enter both your SyncBackSE serial number and your SyncBackPro upgrade serial number.

Copying and pasting is the best way to make sure you're entering the correct serial number. Hold down Ctrl+C keys to copy, and Ctrl+V to paste.

All versions of SyncBack can be safely installed over an existing installation. By doing this, you will ensure any profiles you have created continue to be active.

You can have SyncBackPro, SyncBackSE and SyncBackFree installed on the same computer at the same time, but do not install them into the same folder!

Please be aware that uninstalling may delete your profiles. You may want to export them (Export / Import->Export Profile) before uninstalling.

* In some situations, clicking on the "X" icon on the SyncBack window only minimizes the program window, and not actually closing the program. From the main SyncBack program window, look for the icon/button "Exit" located at the far right of the Icon bar in the program. Click on that to fully close the program.