To make a backup of your profile use the Export/Import tab > Export Profile button available in V9 (or newer) version (or Profiles > Export Profile menu item available in V8 (or older) versions of SyncBack).
You can also export profiles using the -export command line parameter (see the Help file for details). SyncBackPro/SE (but not SyncBackFree) can also be configured to automatically backup all your profiles on exit (select burger menu > Global Settings > Settings Backup, and configure as appropriate in V9 (or newer) version (or Preferences > Options > Expert tab in V8 (or older) version)).
This article has more details on backing up your profiles:
In current versions of SyncBack, profile settings are stored in files (the registry is not used). Those files are by default stored in the users private local Application Data folder. This is typically (for pre-Vista versions of Windows):
C:\Documents and Settings\username\Local Settings\Application Data\2BrightSparks\SyncBack
or (for Vista and later):
(In all cases, adjust the final folder, e.g. SyncBackPro if using the Pro version)
It is also possible to select the equivalent 'roaming' version of the Application Data location for that user. The roaming details are as stored in the user area of the registry, and are extracted therefrom. Configuration of that location is a system issue / the user's or administrator's responsibility: all SyncBack does is ask where it is, and try to use it.
It is possible to switch profile storage to a common/shared location - namely the same folder as the SyncBack executable - the following article has details:
With SyncBackPro/SE V9 (or newer) version, it is possible to specify a folder to store the profiles under:
burger menu > Global Settings > Settings > 'A specific folder' setting
With SyncBackPro/SE V8 (or older) version configure a specific folder under:
Preferences > Options > Settings > 'The folder to use for Profile settings'
Optionally, you can enable the option 'Only Use this folder for settings. Do not use other folders' to use profiles stored only in that specific folder (but not from the default storage location). Note the above option is not supported in SyncBackFree.
If contemplating switching profile storage, you should note that all profiles store Last Run (etcetera) details inside themselves, and are thus re-written to the storage location each run (also, during normal Modification). It is thus a requirement if using this storage location that all users need write access to this folder, which they may not have by default (and if the program detects that, it will disable that option). Profiles can optionally be password-protected against being Modified or Deleted if you wish (Modify > Expert > Misc. section), but write access is still required to store Last Run info, etc.
SyncBack V3 freeware (now discontinued/unsupported: information provided for legacy reasons only)
Profile settings are stored in the registry and files. The files are in the same directory that SyncBack V3 freeware is installed to. The registry location is: